The DC Defenders (4-1) will take on the Michigan Panthers (3-2) in a interconference matchup of winning teams in this Defenders vs. Panthers prediction. This will be their only meeting this season as the Defenders play in the XFL Conference and the Panthers are on the USFL side. The Defenders just won a 37-33 shootout on the road against Arlington, while the Panthers are coming off a 32-27 road loss against St. Louis. Kickoff is set for 12:00 EST and can be found on ESPN. Keep reading to see our... Read more

We have an intriguing nonconference showdown as the DC Defenders get ready to battle it out with the Michigan Panthers in Week 6 action. The Defenders vs. Panthers prediction is set to take place at Ford Field on May 4th at 12:00 PM ET, this game, airing on ESPN promises an interesting matchup. The Defenders (4-1) are coming off a 37-33 road win against the Arlington Renegades in Week 5 on Sunday while the Panthers (3-0) are coming off a 32-27 road loss in Week 5 against the St. Louis Battlehawk... Read more