#105 Buffalo
#106 Detroit

Thursday November 24, 2022
at 12:30pm EST

9 Free Predictions

We searched the web and found all of the free predictions available for this game.



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The Detroit Lions (4-6) will host the Buffalo Bills (7-3) on Thanksgiving Day. This will be the first head-to-head meeting between these teams since 2018. I am on a 14-6 (70%) Best Bet run, including four of my last five. Grab today's top play here.  The team to beat according to oddsmakersThe Buffalo Bills are favored to win the Super Bowl this season with +450 odds according to Draft Kings. The Bills jumped out to a 6-1 start this season before suffering back-to-back three-point upset losses t... Read more



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The Buffalo Bills and the Detroit Lions will face off inside of Ford Field on Thursday afternoon in some Week 12 action. The Bills are second in the AFC East with a 7-3 record so far and are coming off a 31-23 “home” win in Detroit against the Cleveland Browns on Sunday. The Lions are second in the NFC North with a 4-6 record so far this season and are on a three-game winning streak after a 31-18 road win on Sunday against the New York Giants.  Buffalo Staying in DetroitThe Buffalo Bills have be... Read more



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Buffalo Bills at Detroit Lions 11/24/22 - NFL Picks & Predictions Eddie Mon, 11/21/2022 - 22:52 In the first game of a Thanksgiving holiday NFL tripleheader, the Buffalo Bills will invade Ford Field to take on the Detroit Lions. The Bills (7-3) are tied with Miami atop the AFC East Division standings and rank second in the league in total offense at 417 yards per game. On Sunday, Buffalo scored 19 unanswered points to earn a 31-23 home victory versus Cleveland. The Bills averaged 5.2 yards per c... Read more



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Heading into November, the Detroit Lions resembled a train wreck. Entering their traditional Thanksgiving Day game, the Lions are suddenly on the fast track to playing meaningful games in December. Read more



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Our NFL experts predict, pick and preview the Buffalo Bills vs. Detroit Lions Thanksgiving game with kickoff time, TV channel and spread. Read more



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Read about NFL Thanksgiving picks and odds for Thursday, Nov. 24, 2022, including betting predictions for Bill vs. Lions, Giants vs. Cowboys and Patriots vs. Vikings. Read more



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The Buffalo Bills and Detroit Lions meet Thursday in week 12 NFL action at Ford Field. The Buffalo Bills have won 5 of their last 7 games. The Detroit Lions look to build on their 3-game winning streak. The Buffalo Bills have won 3 of their last 5 road games. Josh Allen is completing 64.7 … Read the rest of "Detroit Lions vs Buffalo Bills 11/24/22 NFL Picks, Predictions, Odds" at Sports Chat Place Read more



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Detroit Lions (4-6) vs Buffalo Bills (7-3) Game Info: Thursday, November 24, 2022 at 12:30 pm (Ford Field) Betting Odds: Detroit Lions +9.5 -- Over/Under: 54.5 Click Here for the Latest Odds Where to Watch: CBS Stream live sports and exclusive originals on ESPN+. Sign up now! The Buffalo Bills and Detroit Lions face off on Thursday in the Annual Thanksgiving NFL game at Ford Field.  The Bills will be playing their second game in a row at Ford Field after last week's game was moved to Detroit bec... Read more