#487 San Francisco
#488 Denver

Sunday September 25, 2022
at 8:20pm EDT

7 Free Predictions

We searched the web and found all of the free predictions available for this game.



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WINNING IS EASY WHEN YOU HAVE THE BEST PICKS New York was shutout by Milwaukee on Wednesday to continue our losing skid. However, the NFL is back Thursday and a strong pick gets up back on track for a long weekend of collegeĀ  and Pro football that will increase your bankrolls when having confidence in my strong gridiron selections. NOTE: Comes with a profit guarantee. Win or get the money back in credit.   The San Francisco 49ers are currently 1-1 this season and are coming off a 27-7 home... Read more



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This Sunday night the (1-1) San Francisco 49ers and the (1-1) Denver Broncos will match up in the third week of the 2022 NFL season. Kick-off will be at 8:20 PM EST inside Empower Field at Mile High. Both of these teams have had an interesting start to their season, as they are both (1-1) and dealing with a ton of injuries. The San Francisco 49ers are coming into this one after taking down the Seattle Seahawks, 27-7. They did lose their starting quarterback Trey Lance for the season, as he suffe... Read more



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In the past nine months, Jimmy Garoppolo nearly led San Francisco to the Super Bowl, had surgery on his throwing shoulder, lost his job to Trey Lance and was shopped to other teams before the 49ers reworked his contract to be the backup. Read more



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San Francisco 49ers at Denver Broncos 9/25/22 - NFL Picks & Predictions David Mon, 09/19/2022 - 18:39 The San Francisco Giants visit Empower Field at Mile High to play the Denver Broncos on NFL Sunday Night Football. San Francisco improved to 1-1 following its 27-7 victory over the Seattle Seahawks on Sunday. San Francisco starting quarterback Trey Lance was carted off the field with a season-ending injured ankle but veteran Jimmy Garoppolo came on and led the 49ers to the victory. San Francisco... Read more



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Our NFL experts predict, pick and preview the San Francisco 49ers vs. Denver Broncos Sunday night game, with kickoff time, TV channel and spread. Read more



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Read about the big NFL betting model edge for 49ers vs. Broncos on Sunday, Sept. 25, 2022. Read more



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