On Tuesday, the San Francisco Giants will play the Chicago Cubs at Wrigley Field, and we have you ready to go with our Giants vs. Cubs prediction. First pitch is at 7:40 p.m. ET. San Francisco and Chicago met seven times last season. The Giants won four matchups, but are 4-6 in their last ten meetings with the Cubs. The total was split 5-5 in those ten games. If you want the Giants vs. Cubs prediction, read on and check out our MLB Predictions to beat the sportsbooks! *Article published before t... Read more

This week in Major League Baseball is full of heavyweight matchups, and we'll look at game one in one of those with our San Francisco Giants vs. Chicago Cubs prediction. The San Francisco Giants (22-14) have been off to a fantastic start in 2025, and with all of their stars standing up consistently, this is a team that's making a statement that they are here to stay in the National League West. On Monday they begin a series with another loaded squad in the Chicago Cubs (22-14), a team that is fi... Read more

Get our free Baseball betting pick for the Chicago Cubs vs San Francisco Giants matchup and gain an edge as a Baseball bettor. Read more

Chicago Cubs (22-14) vs San Francisco Giants (22-14) Game Info: Tuesday, May 6, 2025 at 7:40 pm (Wrigley Field) J. Verlander (R) vs C. REA (R) Betting Odds: Chicago Cubs -148 / San Francisco Giants +124 --- Over/Under: 8 Click Here for the Latest Odds Where to Watch: MLB.TV The San Francisco Giants and the Chicago Cubs meet Tuesday in MLB action from Wrigley Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs. Chicago... Read more