San Diego (15-4) will be trying to increase their lead in the NL West when they visit Daikin Park on Saturday night to face Houston (8-10) in the second game of their three-game interleague series at 7:10 PM. ET. Read on to find out which team picks up the win in this Padres vs. Astros prediction and try our Free MLB Picks. Michael King, 3-0, 2.42 ERA, will get the start for the Padres. The Astros will counter with Hayden Wesneski, 1-0, 4.00 ERA. Houston and San Diego split their last 10 meeting... Read more

The MLB action continues on Saturday with an interleague clash between the San Diego Padres (15-5) and the Houston Astros (9-10), and we’ve got you covered with our Padres vs. Astros prediction. Below I’ll dive into each team’s recent form and break down the starting pitching matchup, before concluding with picks and predictions on this contest that gets underway at 7:10 ET from Daikin Park in Houston, TX. Read on for free MLB picks on this game, and check out that link for other game breakdowns... Read more

Get our free Baseball betting pick for the Houston Astros vs San Diego Padres matchup and gain an edge as a Baseball bettor. Read more

The Padres are -120 favorites vs the Astros Padres vs Astros Over / Under today: 8 Runs Padres / Astros TV Channel: FS1 | SCHN | PDTV The San Diego Padres (-120) visit Minute Maid Park to take on the Houston Astros (+100) on Saturday, April 19, 2025. First pitch is scheduled for 7:10pm EDT in Houston, TX, TX. This season, the Padres are 15-5 against the spread (ATS), while the Astros are 9-10 ATS. Padres vs Astros Starting Pitchers Today: Padres starting pitcher: Michael King 3-0, 2.38 ERA Astro... Read more

Houston Astros (9-10) vs San Diego Padres (15-5) Game Info: Saturday, April 19, 2025 at 7:10 pm (Daikin Park) M. King (R) vs H. Wesneski (R) Betting Odds: Houston Astros +105 / San Diego Padres -125 --- Over/Under: 8.5 Click Here for the Latest Odds Where to Watch: FS1 In this article we will formulate a Padres vs Astros prediction for this MLB game on Saturday, April 19th at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup.  San Diego Padres Betting Previe... Read more