Seattle Mariners (8-8) vs. Cincinnati Reds (8-8)  The 2025 Major League Baseball continues Wednesday, April 16, with the interleague showdown at Great American Ball Park in Cincinnati, Ohio, so we have prepared the best Mariners vs. Reds prediction along with the latest odds update.    It’s the middle game of a three-game series, and Tuesday’s opener has been excluded from the analysis. Both teams enjoyed a day off on Monday, hoping to extend their good run of form when they lock horns in Cincin... Read more

The Reds play host to the Mariners in an interleague affair, so check out the full Seattle Mariners vs. Cincinnati Reds prediction. The Reds are hot and snapped the Mariners four-game win streak in winning Game 1 of this series. The first pitch is scheduled for 6:40 pm EST, so continue reading to get the full score info and other free MLB picks for the Seattle Mariners vs. Cincinnati Reds prediction. The Reds are a slight home underdog in Game 2 at +100 with the total sitting at 8.5 runs. Pitchi... Read more

Get our free Baseball betting pick for the Cincinnati Reds vs Seattle Mariners matchup and gain an edge as a Baseball bettor. Read more

At Great American Ball Park on Wednesday, the Cincinnati Reds (three consecutive wins) play the Seattle Mariners (four victories in a row) at 6:40 p.m. ET. The Reds are an underdog (+104 on the moneyline to win) when they square off against the Mariners (-123). The Seattle Mariners will hand the ball to Bryce Miller (0-2, 4.50 ERA), who is looking for win No. 1 on the season, and the Reds will turn to Nick Martinez (0-2, 6.06 ERA). The Mariners won their most recent game against the Rangers on S... Read more

The Mariners are -125 favorites vs the Reds Mariners vs Reds Over / Under today: 8.5 Runs Mariners / Reds TV Channel: FDOH | FS1 | RTNW The Seattle Mariners (-125) visit Great American Ball Park to take on the Cincinnati Reds (+105) on Wednesday, April 16, 2025. First pitch is scheduled for 6:40pm EDT in Cincinnati, OH. This season, the Mariners are 8-9 against the spread (ATS), while the Reds are 11-6 ATS. Mariners vs Reds Starting Pitchers Today: Mariners starting pitcher: Bryce Miller 0-2, 4.... Read more

Cincinnati Reds (9-8) vs Seattle Mariners (8-9) Game Info: Wednesday, April 16, 2025 at 6:40 pm (Great American Ball Park) B. Miller (R) vs N. Martinez (R) Betting Odds: Cincinnati Reds +102 / Seattle Mariners -122 --- Over/Under: 8.5 Click Here for the Latest Odds Where to Watch: FS1 In this article, we will formulate a Mariners vs Reds prediction for this MLB game on Wednesday, April 16, at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup.... Read more