On Tuesday, the Chicago Cubs and San Diego Padres will play at Petco Park, and we have you ready to go with our Cubs vs. Padres prediction. First pitch from America's Finest City is at 6:40 p.m. PT. Chicago and San Diego met at Wrigley Field earlier this month. The Cubs won the first two games by a combined score of 10-2, and the Padres stole the series finale 8-7. The Friars are 6-4 in their last ten meetings with the Cubs, and the total was split 5-5 in those ten games. If you want the Cubs vs... Read more

Pitching Matchup Chicago: Shota Imanaga (LHP) 2-1, 2.70 ERA  San Diego: Randy Vasquez (RHP) 1-1, 1.72 ERA    In our Cubs vs. Padres prediction, the Chicago Cubs are first in the NL Central with an 11-7 record so far. They are having left-hander Shota Imanaga get the start as he is coming off a losing effort against the Texas Rangers where he threw 5.0 innings and gave up five runs on seven hits with one walk and four strikeouts.    The San Diego Padres are doing a phenomenal job right... Read more

Get our free Baseball betting pick for the San Diego Padres vs Chicago Cubs matchup and gain an edge as a Baseball bettor. Read more

The San Diego Padres (14-3) will attempt to extend a five-game winning streak on Tuesday versus the Chicago Cubs (11-8), with first pitch at 9:40 p.m. ET at PETCO Park. The Cubs are favored (-159 on the moneyline) when they visit the Padres (+135). The scheduled starters are Shota Imanaga (2-1) for the Chicago Cubs, and Randy Vasquez (1-1) for the San Diego Padres. Adrian Morejon (1.0 IP, 0 R, 0 H, 1 K) earned a win in the Padres’ 10-4 victory over the Cubs yesterday. Fernando Tatis Jr. led the... Read more

The Cubs are -145 favorites vs the Padres Cubs vs Padres Over / Under today: 7.5 Runs Cubs / Padres TV Channel: MARQ | PDTV | MLBN The Chicago Cubs (-145) visit Petco Park to take on the San Diego Padres (+120) on Tuesday, April 15, 2025. First pitch is scheduled for 9:40pm EDT in San Diego, CA. This season, the Cubs are 0-0 against the spread (ATS), while the Padres are 0-0 ATS. Cubs vs Padres Starting Pitchers Today: Cubs starting pitcher: Shota Imanaga 2-1, 2.70 ERA Padres starting pitcher: R... Read more

San Diego Padres (14-3) vs Chicago Cubs (11-8) Game Info: Tuesday, April 15, 2025 at 9:40 pm (Petco Park) S. Imanaga (L) vs R. Vasquez (R) Betting Odds: San Diego Padres +120 / Chicago Cubs -142 --- Over/Under: 7.5 Click Here for the Latest Odds Where to Watch: MLB.TV The Chicago Cubs and San Diego Padres meet Tuesday in MLB action at Petco Park. Here’s a Chicago Cubs vs San Diego Padres Prediction. This article will include a Chicago Cubs vs San Diego Padres Pick. Chicago Cubs Betting Preview T... Read more